BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 2, Issue 1 , Pages 41-49, January 2009

A pilot study of the teratogenicity of vagus nerve stimulation in a rabbit model

  • Ingela Danielsson, MD, PhD

      Affiliations

    • Cyberonics, Inc, Houston, Texas
    • Corresponding Author InformationCorrespondence: Dr. Ingela Danielsson, 100 Cyberonics Blvd., Houston, TX 77058.
    • ,
  • Laurence Lister, BS

      Affiliations

    • Toxikon, Inc, Bedford, Massachusetts

Received 26 October 2007; received in revised form 11 June 2008; accepted 12 June 2008. published online 10 October 2008.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

 The results of the teratogenicity study were presented in poster form at the 57th meeting of the American Epilepsy Society, December 5-10, 2003, in Boston, Massachusetts, Harden, CL (Comprehensive Epilepsy Center, Weill Medical College of Cornell University, New York, NY) High-dose vagus nerve stimulation does not cause teratogenicity in animals.

 Cyberonics, Inc, manufacturer of the VNS Therapy System, compensated Toxikon, Corporation of Bedford, Massachusetts, for performing this reproductive and developmental toxicity screening test. Mr. Laurence Lister, an author of this article, is an employee of Toxikon Corporation, which was contracted to perform the Reproductive Screening study; Mr. Lister received no direct compensation from Cyberonics for directing the study. Ingela Danielsson, MD, PhD, an author of this article, is a stockholder of Cyberonics, Inc.

PII: S1935-861X(08)00043-0

doi:10.1016/j.brs.2008.06.008

BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 2, Issue 1 , Pages 41-49, January 2009

Article Tools