BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 2, Issue 1 , Pages 36-40 , January 2009

Corticomotor responses to triple-pulse transcranial magnetic stimulation: Effects of interstimulus interval and stimulus intensity

  • Paul Sacco, PhD

      Affiliations

    • School of Health and Bioscience, University of East London, London, United Kingdom
    • Corresponding Author InformationCorrespondence: Dr. Paul Sacco, School of Health and Bioscience, University of East London, Stratford Campus, London E15 4LZ, United Kingdom.
    • ,
  • Duncan Turner, PhD

      Affiliations

    • School of Health and Bioscience, University of East London, London, United Kingdom
    • ,
  • John Rothwell, PhD

      Affiliations

    • Institute of Neurology, University College London, London, United Kingdom
    • ,
  • Gary Thickbroom, PhD

      Affiliations

    • Centre for Neuromuscular and Neurological Disorders, University of Western Australia, Perth, Australia

Received 29 January 2008 ,Revised 26 June 2008 ,Accepted 27 June 2008.

References 

  1. Tokimura H, Ridding MC, Tokimura Y, Amassian VE, Rothwell JC. Short latency facilitation between pairs of threshold magnetic stimuli applied to human motor cortex. Electroencephalogr Clin Neurophysiol. 1996;101(4):263–272
  2. Ziemann U, Tergau F, Wassermann EM, Wischer S, Hildebrandt J, Paulus W. Demonstration of facilitatory I wave interaction in the human motor cortex by paired transcranial magnetic stimulation. J Physiol. 1998;511(Pt 1):181–190
  3. Ilic TV, Meintzschel F, Cleff U, Ruge D, Kessler KR, Ziemann U. Short-interval paired-pulse inhibition and facilitation of human motor cortex: the dimension of stimulus intensity. J Physiol. 2002;545(Pt 1):153–167
  4. Kernell D, Chien-Ping WU. Responses of the pyramidal tract to stimulation of the baboon's motor cortex. J Physiol. 1967;191(3):653–672
  5. Di Lazzaro V, Oliviero A, Profice P, et al. Descending spinal cord volleys evoked by transcranial magnetic and electrical stimulation of the motor cortex leg area in conscious humans. J Physiol. 2001;537(Pt 3):1047–1058
  6. Thickbroom GW, Byrnes ML, Edwards DJ, Mastaglia FL. Repetitive paired-pulse TMS at I-wave periodicity markedly increases corticospinal excitability: a new technique for modulating synaptic plasticity. Clin Neurophysiol. 2006;117(1):61–66
  7. Hamada M, Hanajima R, Terao Y, et al. Origin of facilitation in repetitive, 1.5 ms interval, paired pulse transcranial magnetic stimulation (rPPS) of the human motor cortex. Clin Neurophysiol. 2007;118(7):1596–1601
  8. Ziemann U. LTP-like plasticity in human motor cortex. Suppl Clin Neurophysiol. 2004;57:702–707
  9. Di Lazzaro V, Restuccia D, Oliviero A, et al. Magnetic transcranial stimulation at intensities below active motor threshold activates intracortical inhibitory circuits. Exp Brain Res. 1998;119(2):265–268
  10. Ziemann U, Tergau F, Wischer S, Hildebrandt J, Paulus W. Pharmacological control of facilitatory I-wave interaction in the human motor cortex: a paired transcranial magnetic stimulation study. Electroencephalogr Clin Neurophysiol. 1998;109(4):321–330
  11. Hanajima R, Ugawa Y, Terao Y, et al. Mechanisms of intracortical I-wave facilitation elicited with paired-pulse magnetic stimulation in humans. J Physiol. 2002;538(Pt 1):253–261
  12. Amassian V, Rothwell J, Cracco R, et al. What is excited by near-threshold twin magnetic stimuli over human cerebral cortex?. J Physiol. 1998;506P:122P
  13. Hanajima R, Ugawa Y, Terao Y, et al. Paired-pulse magnetic stimulation of the human motor cortex: differences among I waves. J Physiol. 1998;509(Pt 2):607–618
  14. Di Lazzaro V, Rothwell JC, Oliviero A, et al. Intracortical origin of the short latency facilitation produced by pairs of threshold magnetic stimuli applied to human motor cortex. Exp Brain Res. 1999;129(4):494–499
  15. Jankowska E, Padel Y, Tanaka R. Disynaptic inhibition of spinal motoneurones from the motor cortex in the monkey. J Physiol. 1976;258(2):467–487
  16. Mercuri B, Wassermann EM, Ikoma K, et al. Effects of transcranial electrical and magnetic stimulation on reciprocal inhibition in the human arm. Electroencephalogr Clin Neurophysiol. 1997;105(2):87–93
  17. Ziemann U, Rothwell JC, Ridding MC. Interaction between intracortical inhibition and facilitation in human motor cortex. J Physiol. 1996;496(Pt 3):873–881
  18. Di Lazzaro V, Thickbroom GW, Pilato F, et al. Direct demonstration of the effects of repetitive paired-pulse transcranial magnetic stimulation at I-wave periodicity. Clin Neurophysiol. 2007;118(6):1193–1197
  19. Hamada M, Hanajima R, Terao Y, et al. Quadro-pulse stimulation is more effective than paired-pulse stimulation for plasticity induction of the human motor cortex. Clin Neurophysiol. 2007;118:2672–2682

PII: S1935-861X(08)00290-8

doi: 10.1016/j.brs.2008.06.255

BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 2, Issue 1 , Pages 36-40 , January 2009

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