BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 2, Issue 3 , Pages 138-148 , July 2009

Intraoperative neurophysiologic mapping of the central cortical region for epidural electrode placement in the treatment of neuropathic pain by motor cortex stimulation

  • Jean-Pascal Lefaucheur, MD, PhD

      Affiliations

    • Corresponding Author InformationCorrespondence: Prof. Jean-Pascal Lefaucheur, Service de Physiologie, Explorations Fonctionnelles, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris, 51, avenue de Lattre de Tassigny, 94010 Créteil, France.
    • ,
  • Daniel Ciampi de Andrade, MD

Received 1 August 2008 ,Revised 19 January 2009 ,Accepted 20 January 2009.

References 

  1. Cruccu G, Aziz TZ, Garcia-Larrea L, et al. EFNS guidelines on neurostimulation therapy for neuropathic pain. Eur J Neurol. 2007;14:952–970
  2. Tsubokawa T, Katayama Y, Yamamoto T, Hirayama T, Koyama S. Treatment of thalamic pain by chronic motor cortex stimulation. Pacing Clin Electrophysiol. 1991;14:131–134
  3. Tsubokawa T, Katayama Y, Yamamoto T, Hirayama T, Koyama S. Chronic motor cortex stimulation for the treatment of central pain. Acta Neurochir Suppl. 1991;52:137–139
  4. Tsubokawa T, Katayama Y, Yamamoto T, et al. Chronic motor cortex stimulation in patients with thalamic pain. J Neurosurg. 1993;78:393–401
  5. Meyerson BA, Lindblom U, Lind G, et al. Motor cortex stimulation as treatment of trigeminal neuropathic pain. Acta Neurochir Suppl. 1993;58:150–153
  6. Nguyen JP, Lefaucheur JP, Decq P, et al. Chronic motor cortex stimulation in the treatment of central of neuropathic pain: correlations between clinical, electrophysiological and anatomical data. Pain. 1999;82:245–251
  7. Mertens P, Nuti C, Sindou M, et al. Precentral cortex stimulation for the treatment of central neuropathic pain: results of a prospective study in a 20-patient series. Stereotact Funct Neurosurg. 1999;73:122–125
  8. Rasche D, Ruppolt M, Stippich C, Unterberg A, Tronnier VM. Motor cortex stimulation for long-term relief of chronic neuropathic pain: a 10 year experience. Pain. 2006;121:43–52
  9. Nguyen JP, Velasco F, Brugières P, et al. Treatment of chronic neuropathic pain by motor cortex stimulation: results of a bicentric controlled crossover trial. Brain Stim. 2008;1:89–96
  10. Velasco F, Argüelles C, Carrillo-Ruiz JD, et al. Efficacy of motor cortex stimulation in the treatment of neuropathic pain: a randomized double-blind trial. J Neurosurg. 2008;108:698–706
  11. Nguyen JP, Lefaucheur JP, Le Guerinel C, et al. Motor cortex stimulation in the treatment of central and neuropathic pain. Arch Med Res. 2000;31:263–265
  12. Sol JC, Casaux J, Roux FE, et al. Chronic motor cortex stimulation for phantom limb pain: correlations between pain relief and functional imaging studies. Stereotact Funct Neurosurg. 2001;77:172–176
  13. Pirotte B, Voordecker Ph, Neugroschl C, et al. Combination of functional magnetic resonance image-guided neuronavigation and intraoperative cortical brain mapping improves targeting of motor cortex stimulation in neuropathic pain. Neurosurgery. 2005;56(Suppl 2):344–359
  14. Nguyen JP, Lefaucheur JP, Keravel Y. Motor cortex stimulation. In:  Simpson BA editors. Electrical stimulation and the relief of pain: pain research and clinical management, vol. 15. Amsterdam: Elsevier Science; 2003;p. 197–209
  15. Brown JA, Barbaro NM. Motor cortex stimulation for central and neuropathic pain: current status. Pain. 2003;104:431–435
  16. Canavero S, Bonicalzi V. Extradural cortical stimulation for central pain. Acta Neurochir Suppl. 2007;97:27–36
  17. Lazorthes Y, Sol JC, Fowo S, Roux FE, Verdié JC. Motor cortex stimulation for neuropathic pain. Acta Neurochir Suppl. 2007;97:37–44
  18. Cioni B, Meglio M. Motor cortex stimulation for chronic non-malignant pain: current state and future prospects. Acta Neurochir Suppl. 2007;97:45–49
  19. Saitoh Y, Yoshimine T. Stimulation of primary motor cortex for intractable deafferentation pain. Acta Neurochir Suppl. 2007;97:51–56
  20. Lima MC, Fregni F. Motor cortex stimulation for chronic pain: systematic review and meta-analysis of the literature. Neurology. 2008;70:2329–2337
  21. Fontaine D, Hamani C, Lozano A. Efficacy and safety of motor cortex stimulation for chronic neuropathic pain: critical review of the literature. J Neurosurg. 2008 Nov 7;[Published in Epub ahead of print]
  22. Penfield W, Rasmussen T. The cerebral cortex of man. A clinical study of localization of function. New York: MacMillan; 1950;
  23. Woolsey CN, Erickson TC, Gilson WE. Localization in somatic sensory and motor areas of human cerebral cortex as determined by direct recording of evoked potentials and electrical stimulation. J Neurosurg. 1979;51:476–506
  24. Nii Y, Uematsu S, Lesser RP, Gordon B. Does the central sulcus divide motor and sensory functions? Cortical mapping of human hand areas as revealed by electrical stimulation through subdural grid electrodes. Neurology. 1996;46:360–367
  25. Rademacher J, Bürgel U, Geyer S, et al. Variability and asymmetry in the human precentral motor system. A cytoarchitectonic and myeloarchitectonic brain mapping study. Brain. 2001;124:2232–2258
  26. Roux FE, Ibarrola D, Lazorthes Y, Berry I. Chronic motor cortex stimulation for phantom limb pain: a functional magnetic resonance imaging study: technical case report. Neurosurgery. 2001;48:681–687
  27. Roux FE, Ibarrola D, Tremoulet M, et al. Methodological and technical issues for integrating functional magnetic resonance imaging data in a neuronavigational system. Neurosurgery. 2001;49:1145–1157
  28. Pirotte B, Neugroschl C, Metens T, et al. Comparison of functional MR imaging guidance to electrical cortical mapping for targeting selective motor cortex areas in neuropathic pain: a study based on intraoperative stereotactic navigation. AJNR Am J Neuroradiol. 2005;26:2256–2266
  29. Lefaucheur JP. Use of repetitive transcranial magnetic stimulation in pain relief. Expert Rev Neurother. 2008;8:799–808
  30. Wood CC, Spencer DD, Allison T, et al. Localization of human sensorimotor cortex during surgery by cortical surface recording of somatosensory evoked potentials. J Neurosurg. 1988;68:98–111
  31. Cedzich C, Taniguchi M, Schäfer S, et al. Somatosensory evoked potential phase reversal and direct motor cortex stimulation during surgery in and around the central region. Neurosurgery. 1996;38:962–970
  32. Romstöck J, Fahlbusch R, Ganslandt O, et al. Localisation of the sensorimotor cortex during surgery for brain tumours: feasibility and waveform patterns1 of somatosensory evoked potentials. J Neurol Neurosurg Psychiatry. 2002;72:221–229
  33. Baumgartner C, Barth DS, Levesque MF, Sutherling WW. Functional anatomy of human hand sensorimotor cortex from spatiotemporal analysis of electrocorticography. Electroencephalogr Clin Neurophysiol. 1991;78:56–65
  34. Mogilner AY, Rezai AR. Epidural motor cortex stimulation with functional imaging guidance. Neurosurg Focus. 2001;11:E4
  35. Henderson JM, Boongird A, Rosenow JM, LaPresto E, Rezai AR. Recovery of pain control by intensive reprogramming after loss of benefit from motor cortex stimulation for neuropathic pain. Stereotact Funct Neurosurg. 2004;82:207–213
  36. Brown JA, Pilitsis JG. Motor cortex stimulation for central and neuropathic facial pain: a prospective study of 10 patients and observations of enhanced sensory and motor function during stimulation. Neurosurgery. 2005;56:290–297
  37. Nuti C, Peyron R, Garcia-Larrea L, et al. Motor cortex stimulation for refractory neuropathic pain: four year outcome and predictors of efficacy. Pain. 2005;118:43–52
  38. Berger MS, Ojemann GA, Lettich E. Neurophysiological monitorage during astrocytoma surgery. Neurosurg Clin N Am. 1990;1:65–80
  39. Taniguchi M, Cedzich C, Schramm J. Modification of cortical stimulation for motor evoked potentials under general anesthesia: technical description. Neurosurgery. 1993;32:219–226
  40. Kombos T, Suess O, Kern BC, et al. Comparison between monopolar and bipolar electrical stimulation of the motor cortex. Acta Neurochir (Wien). 1999;141:1295–1301
  41. Maertens de Noordhout A, Born JD, Hans P, et al. Intraoperative localisation of the primary motor cortex using single electrical stimuli. J Neurol Neurosurg Psychiatry. 1996;60:442–444
  42. Bezard E, Boraud T, Nguyen JP, et al. Cortical stimulation and epileptic seizure: a study of the potential risk in primates. Neurosurgery. 1999;45:346–350
  43. Lichtenbelt BJ, Mertens M, Vuyk J. Strategies to optimise propofol-opioid anaesthesia. Clin Pharmacokinet. 2004;43:577–593
  44. Holsheimer J, Lefaucheur JP, Buitenweg JR, et al. The role of intra-operative motor evoked potentials in the optimization of chronic cortical stimulation for the treatment of neuropathic pain. Clin Neurophysiol. 2007;118:2287–2296
  45. Ranck JB. Which elements are excited in electrical stimulation of mammalian central nervous system: a review. Brain Res. 1975;98:417–440
  46. Nowak LG, Bullier J. Axons, but not cell bodies, are activated by electrical stimulation in cortical gray matter: I, evidence from chronaxie measurements. Exp Brain Res. 1998;118:477–488
  47. Nowak LG, Bullier J. Axons, but not cell bodies, are activated by electrical stimulation in cortical gray matter: II, evidence from selective inactivation of cell bodies and axon initial segments. Exp Brain Res. 1998;118:489–500
  48. Manola L, Roelofsen BH, Holsheimer J, et al. Modelling motor cortex stimulation for chronic pain control: electrical potential field, activating functions and responses of simple nerve fibre models. Med Biol Eng Comput. 2005;43:335–343
  49. Manola L, Holsheimer J, Veltink P, et al. Anodal vs cathodal stimulation of motor cortex: a modeling study. Clin Neurophysiol. 2007;118:464–474
  50. Kleiner-Fisman G, Fisman DN, Kahn FI, et al. Motor cortical stimulation for parkinsonism in multiple system atrophy. Arch Neurol. 2003;60:1554–1558
  51. Holsheimer J, Nguyen JP, Lefaucheur JP, et al. Cathodal, anodal or bifocal stimulation of the motor cortex in the management of chronic pain?. Acta Neurochir Suppl. 2007;97:57–66
  52. Delavallée M, Abu-Serieh B, de Tourchaninoff M, Raftopoulos C. Subdural motor cortex stimulation for central and peripheral neuropathic pain: a long-term follow-up study in a series of eight patients. Neurosurgery. 2008;63:101–108
  53. Herregodts P, Stadnik T, De Ridder F, D'Haens J. Cortical stimulation for central neuropathic pain: 3-D surface MRI for easy determination of the motor cortex. Acta Neurochir Suppl. 1995;64:132–135
  54. Pirotte B, Voordecker P, Joffroy F, et al. The Zeiss-MKM system for frameless image-guided approach in epidural motor cortex stimulation for central neuropathic pain. Neurosurg Focus. 2001;11:E3
  55. Arle JE, Shils JL. Motor cortex stimulation for pain and movement disorders. Neurotherapeutics. 2008;5:37–49
  56. Nguyen JP, Keravel Y, Feve A, et al. Treatment of deafferentation pain by chronic stimulation of the motor cortex: report of a series of 20 cases. Acta Neurochir Suppl. 1997;68:54–60
  57. Rainov NG, Fels C, Heidecke V, Burkert W. Epidural electrical stimulation of the motor cortex in patients with facial neuralgia. Clin Neurol Neurosurg. 1997;99:205–209
  58. Rainov NG, Heidecke V. Motor cortex stimulation for neuropathic facial pain. Neurol Res. 2003;25:157–161
  59. Ebel H, Rust D, Tronnier V, Böker D, Kunze S. Chronic precentral stimulation in trigeminal neuropathic pain. Acta Neurochir (Wien). 1996;138:1300–1306
  60. Tirakotai W, Hellwig D, Bertalanffy H, Riegel T. Localization of precentral gyrus in image-guided surgery for motor cortex stimulation. Acta Neurochir Suppl. 2007;97:75–79
  61. Saitoh Y, Shibata M, Hirano S, Hirata M, Mashimo T, Yoshimine T. Motor cortex stimulation for central and peripheral deafferentation pain: report of eight cases. J Neurosurg. 2000;92:150–155
  62. Saitoh Y, Hirano S, Kato A, et al. Motor cortex stimulation for deafferentation pain. Neurosurg Focus. 2001;11:E1
  63. Saitoh Y, Kato A, Ninomiya H, et al. Primary motor cortex stimulation within the central sulcus for treating deafferentation pain. Acta Neurochir Suppl. 2003;87:149–152
  64. Hosomi K, Saitoh Y, Kishima H, et al. Electrical stimulation of primary motor cortex within the central sulcus for intractable neuropathic pain. Clin Neurophysiol. 2008;119:993–1001
  65. Carroll D, Joint C, Maartens N, Shlugman D, Stein J, Aziz TZ. Motor cortex stimulation for chronic neuropathic pain: a preliminary study of 10 cases. Pain. 2000;84:431–437
  66. Smith H, Joint C, Schlugman D, Nandi D, Stein JF, Aziz TZ. Motor cortex stimulation for neuropathic pain. Neurosurg Focus. 2001;11:E2
  67. Nandi D, Smith H, Owen S, Joint C, Stein J, Aziz T. Peri-ventricular grey stimulation versus motor cortex stimulation for post stroke neuropathic pain. J Clin Neurosci. 2002;9:557–561
  68. Hosobuchi Y. Motor cortical stimulation for control of central deafferentation pain. Adv Neurol. 1993;63:215–217
  69. Son UC, Kim MC, Moon DE, Kang JK. Motor cortex stimulation in a patient with intractable complex regional pain syndrome type II with hemibody involvement: case report. J Neurosurg. 2003;98:175–179
  70. Yamamoto T, Katayama Y, Hirayama T, Tsubokawa T. Pharmacological classification of central post-stroke pain: comparison with the results of chronic motor cortex stimulation therapy. Pain. 1997;72:5–12
  71. Katayama Y, Fukaya C, Yamamoto T. Poststroke pain control by chronic motor cortex stimulation: neurological characteristics predicting a favorable response. J Neurosurg. 1998;89:585–591
  72. Fukaya C, Katayama Y, Yamamoto T, Kobayashi K, Kasai M, Oshima H. Motor cortex stimulation in patients with post-stroke pain: conscious somatosensory response and pain control. Neurol Res. 2003;25:153–156

PII: S1935-861X(09)00007-2

doi: 10.1016/j.brs.2009.01.002

BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 2, Issue 3 , Pages 138-148 , July 2009

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