BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 2, Issue 4 , Pages 229-233 , October 2009

Cannabis-based treatment induces polarity-reversing plasticity assessed by theta burst stimulation in humans

  • Giacomo Koch, MD, PhD

      Affiliations

    • Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy
    • Centro Europeo per la Ricerca sul Cervello (CERC)/Fondazione Santa Lucia, Rome, Italy
    • Corresponding Author InformationCorrespondence: Dr Giacomo Koch, Stroke Unit, Dipartimento di Neuroscienze, Università Tor Vergata, Viale Oxford 81, 00133 Rome, Italy.
    • ,
  • Francesco Mori, MD

      Affiliations

    • Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy
    • ,
  • Claudia Codecà, MD

      Affiliations

    • Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy
    • ,
  • Hajime Kusayanagi, MD

      Affiliations

    • Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy
    • ,
  • Fabrizia Monteleone, MD

      Affiliations

    • Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy
    • ,
  • Fabio Buttari, MD

      Affiliations

    • Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy
    • ,
  • Stefania Fiore, MD

      Affiliations

    • Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy
    • ,
  • Giorgio Bernardi, MD

      Affiliations

    • Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy
    • Centro Europeo per la Ricerca sul Cervello (CERC)/Fondazione Santa Lucia, Rome, Italy
    • ,
  • Diego Centonze, MD

      Affiliations

    • Clinica Neurologica, Dipartimento di Neuroscienze, Università Tor Vergata, Rome, Italy
    • Centro Europeo per la Ricerca sul Cervello (CERC)/Fondazione Santa Lucia, Rome, Italy

Received 1 January 2009 ,Revised 26 February 2009 ,Accepted 2 March 2009.

References 

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  5. Huang YZ, Edwards MJ, Rounis E, Bhatia KP, Rothwell JC. Theta burst stimulation of the human motor cortex. Neuron. 2005;45(2):201–206
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  12. Gentner R, Wankerl K, Reinsberger C, Zeller D, Classen J. Depression of human corticospinal excitability induced by magnetic theta-burst stimulation: evidence of rapid polarity-reversing metaplasticity. Cereb Cortex. 2008;18(9):2046–2053
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  14. Siebner HR, Lang N, Rizzo V, et al. Preconditioning of low-frequency repetitive transcranial magnetic stimulation with transcranial direct current stimulation: evidence for homeostatic plasticity in the human motor cortex. J Neurosci. 2004;24(13):3379–3385
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 This investigation was supported by the Italian National Ministero dell'Università e della Ricerca, by the Italian National Ministero della Salute to GK and DC, by the Fondazione Italiana Sclerosi Multipla (FISM) to DC, and by the Agenzia Spaziale Italiana to GB.

PII: S1935-861X(09)00013-8

doi: 10.1016/j.brs.2009.03.001

BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 2, Issue 4 , Pages 229-233 , October 2009

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