BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 3, Issue 3 , Pages 177-180 , July 2010

Bupropion decreases resting motor threshold: A case report

  • Mustafa A. Mufti

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia
  • ,
  • Paul E. Holtzheimer III

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia
    • Corresponding Author InformationCorrespondence: Paul E. Holtzheimer III, MD, 101 Woodruff Circle NE, Suite 4000, Atlanta, GA 30322.
  • ,
  • Charles M. Epstein

      Affiliations

    • Department of Neurology, Emory University School of Medicine, Atlanta, Georgia
  • ,
  • Sinéad C. Quinn

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia
  • ,
  • Nancie Vito

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia
  • ,
  • William M. McDonald

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia

Received 17 April 2009 ,Revised 1 July 2009 ,Accepted 14 August 2009.

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 This work was funded through a grant from the National Institute of Mental Health (NIMH) (R01 MH069886).

 Dr. Mufti reports no financial relationships or potential conflicts of interest.

 Over the past 5 years, Dr. Holtzheimer has received: grant funding from National Alliance for Research on Schizophrenia and Depression (NARSAD), NIMH, and the Greenwall Foundation; consulting fees from Advanced Neuromodulation Systems/St. Jude Medical, AstraZeneca, Shaw Science and Tetragenex; honoraria from CME Outfitters, Inc. (Cyberonics); Cerebrio, Inc. (Boerhinger-Ingelheim); CME LLC, Inc. (Bristol-Myers Squibb); Letters and Sciences (Bristol-Myers Squibb); and Prescott Medical Communications Group (Forest).

 Dr. Epstein consults for Neuronetics, Inc. Through Emory University he holds patents for the Neuronetics transcranial magnetic stimulator that is used in the NIMH trial, but has no involvement in the choice of equipment, protocol design, treatment, or data analysis for that trial. He is Principal Investigator on a VA study of depression that uses non-Neuronetics equipment. He receives grant support from GlaxoSmithKline, Inc.

 Ms. Quinn and Ms. Vito report no financial relationships or potential conflicts of interest.

 Dr. McDonald reports that he serves on the Executive Board of the Georgia Psychiatric Physicians Association and is Director of the Fuqua Center for Late-Life Depression that advocates for geriatric psychiatry. He is also the Chair of the American Psychiatric Association (APA) Committee on Electroconvulsive Therapy and Other Electromagnetic Therapies and a member of the APA Council on Research; and reports Consultant/Speaker Honorarium from Myriad, Bristol-Myers Squibb, and Janssen. He has received grant support from Boehinger Ingelheim and Neuronetics and was an investigator in a trial sponsored by Janssen. He is currently Principal Investigator on an NIMH study that uses Neuronetics' transcranial magnetic stimulators. Dr. McDonald works for Emory University that holds a patent for the transcranial magnetic stimulator that is used in the NIMH trial. He is also in an National Institute of Neurological Disorders and Stroke (NINDS) trial that is evaluating medication donated by Smith Kline (Paxil CR) and Wyeth (Effexor XR).

PII: S1935-861X(09)00083-7

doi: 10.1016/j.brs.2009.08.001

BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 3, Issue 3 , Pages 177-180 , July 2010