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Intensive HF-rTMS treatment in an ECT resistant bipolar I patient with mixed episode

Dieter Zeeuwsa, Kim De Ryckera, Rudi De Raedtb, Matthieu De Beynea, Chris BaekenaCorresponding Author Informationemail address, Nathalie Vanderbruggena

Received 23 September 2009; received in revised form 14 December 2009; accepted 13 January 2010. published online 11 February 2010.
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Although electroconvulsive shock therapy (ECT) remains a successful treatment strategy in medication-resistant bipolar disorder, not all patients respond well. Here, we report on a successful high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) therapy in a highly treatment-resistant bipolar I patient during a mixed episode. This case illustrates that “combative” HF-rTMS therapy could be a safe and valid treatment alternative for refractory bipolar I patients with mixed episodes.

a Department of Psychiatry, University Hospital, Free University of Brussels, UZBrussel, Brussels, Belgium

b Department of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium

Corresponding Author InformationCorrespondence: Chris Baeken. Department of Psychiatry, University Hospital (UZBrussel), Free University of Brussels (VUB), Laarbeeklaan 101, 1090 Brussels, Belgium.

PII: S1935-861X(10)00015-X

doi:10.1016/j.brs.2010.01.004

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