BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 4, Issue 2 , Pages 112-114, April 2011

Cardiac safety of repetitive transcranial magnetic stimulation in bulimic eating disorders

  • Frederique Van den Eynde

      Affiliations

    • Institute of Psychiatry, King’s College London, London, United Kingdom
    • Corresponding Author InformationCorrespondence: Frederique Van den Eynde, Section of Eating Disorders, P.O. 59, De Crespigny Park, SE5 8AF, London, UK
    • ,
  • Angélica M. Claudino

      Affiliations

    • Institute of Psychiatry, King’s College London, London, United Kingdom
    • Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil
    • ,
  • Iain Campbell

      Affiliations

    • Institute of Psychiatry, King’s College London, London, United Kingdom
    • ,
  • Linda Horrell

      Affiliations

    • Institute of Psychiatry, King’s College London, London, United Kingdom
    • ,
  • Manoharan Andiappan

      Affiliations

    • Institute of Psychiatry, King’s College London, London, United Kingdom
    • ,
  • Daniel Stahl

      Affiliations

    • Institute of Psychiatry, King’s College London, London, United Kingdom
    • ,
  • Ulrike Schmidt

      Affiliations

    • Institute of Psychiatry, King’s College London, London, United Kingdom

Received 19 May 2010; received in revised form 14 June 2010; accepted 16 June 2010. published online 12 July 2010.

Background

Repetitive transcranial magnetic stimulation (rTMS) is increasingly used in research. However, cardiac safety is not routinely assessed.

Objective

This study aims to investigate cardiac safety of rTMS in people with a bulimic eating disorder.

Methods

Thirty-eight people with a bulimic disorder were enrolled in a randomized sham-controlled trial. High frequency rTMS was delivered to the left dorsolateral prefrontal cortex.

Results

rTMS did not alter blood pressure or heart rate.

Conclusions

Our findings indicated that this rTMS paradigm has no cardiac complications as assessed by blood pressure and heart rate. This adds to the emerging literature on the cardiac safety of rTMS.

Keywords: eating disorders, blood pressure, heart rate

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 F.V.d.E. is a research fellow of the Marie Curie Research Training Network INTACT (Individually Tailored Stepped Care for Women with Eating Disorders; MRTN-CT-2006-035988).

 A.M.C. was funded by CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior), Ministry of Education, Brazil, with a postdoctoral grant at the Institute of Psychiatry, King’s College London, during 2008.

PII: S1935-861X(10)00061-6

doi:10.1016/j.brs.2010.06.003

BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation
Volume 4, Issue 2 , Pages 112-114, April 2011

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