Obsessive compulsive disorder (OCD) is characterized by recurrent intrusive thoughts
and impulses (obsessions), followed by repetitive thinking or behavioral acting (compulsions)
which reduces the obsession-associated anxiety level. Without treatment, severity
and daily duration of compulsive symptoms often increase, eventually resulting in
marked social impairment and loss of employment. Psychopharmacological treatment with
serotonin re-uptake inhibitors, and tricyclic antidepressants like clomipramine, which
seems to be as effective as cognitive behavior therapy (CBT) leads to symptom reduction
in 40–70%, and full recovery in approximately 25% of patients [
[1]
]. However, nonresponding patients [
[2]
] are usually severely ill and socially isolated without real chance for substantial
clinical improvement.To read this article in full you will need to make a payment
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References
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Article info
Publication history
Published online: March 10, 2016
Received:
February 17,
2016
Identification
Copyright
© 2016 Elsevier Inc. All rights reserved.
