Introduction: Physiological brain aging is characterized by synaptic dysfunctions with consequent
neuroplasticity alterations. A challenge in neuroscience is to identify the patterns
of neuronal activity underlying the neuroplasticity changes during the life span and
to extract the neurophysiological markers on the cortical areas firstly impacted by
physiological aging, i.e. prefrontal cortex. Our study aimed to investigate the age-dependent
neuroplasticity mechanisms at cortical and behavioural levels.
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© 2017 Published by Elsevier Inc.