Abstract| Volume 10, ISSUE 2, P511, March 2017

Reduced neuroplasticity in the dorsolateral prefrontal cortex in patients with depression as indexed by paired associative stimulation paradigm combined with EEG

      Introduction: Dysfunction of neuroplasticity may be one of the pathophysiological mechanisms underlying major depression. We have previously established methods to assess neuroplastic potentiation from the dorsolateral prefrontal cortex (DLPFC) using a paired associative stimulation (PAS) paradigm, which combines preceding peripheral nerve stimulation and subsequent transcranial magnetic stimulation (TMS), combined electroencephalography (EEG). Here, we aimed to investigate a PAS potentiation from the DLPFC in patients with depression compared to healthy controls.
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