Transcranial magnetic stimulation (TMS) is a popular method for measuring motor cortical
excitability in healthy and clinical populations, and is often used as an outcome
measure to explore changes following an intervention. It is therefore important that
the reliability of these measures is extensively examined and demonstrated. Several
studies have sought to explore this [
1
,
2
,
3
,
4
,
5
], and have typically included assessment of reliability across 2–3 sessions for the
following measures: motor threshold (MT); TMS recruitment/input output (IO) curves;
short interval intracortical inhibition (SICI); and intracortical facilitation (ICF).
These have revealed varying degrees of reliability across the different parameters
[
[6]
]. Here we report the results of an in-depth exploration of TMS measures over an extensive
testing period of 8 sessions. We also explore the impact of different data analysis
processes.To read this article in full you will need to make a payment
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References
- Comparison of transcranial magnetic stimulation measures obtained at rest and under active conditions and their reliability.J Neurosci Meth. 2012; 205: 65-71
- Test-retest reliability of single and paired pulse transcranial magnetic stimulation parameters in healthy subjects.J Neurol Sci. 2016; 362: 209-216
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- Reproducibility of single-pulse, paired-pulse, and intermittent theta-burst TMS measures in healthy aging, Type-2 diabetes, and alzheimer's disease.Front Aging Neurosci. 2017; 9: 263
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- Reliability and minimal detectable change of transcranial magnetic stimulation outcomes in healthy adults: a systematic review.Brain Stimul. 2017; 10: 196-213
- Intra-subject consistency and reliability of response following 2 mA transcranial direct current stimulation.Brain Stimulation. 2016; 9: 819-825
- Intraclass correlations - theres more there than meets the eye.Psychol Bull. 1983; 93: 586-595
Article info
Publication history
Published online: August 18, 2018
Accepted:
August 16,
2018
Received:
July 26,
2018
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.