Over the past decade there has been significant advancement in understanding the multitude
of ways naltrexone interacts with human physiology. The two main theories purported
in literature are suppression of cytokine production by glial cells and transient
blockade of the mu- opioid receptor. This case report highlights a chronic pain patient
that sustained a wean from high dose opioid regimen utilizing low dose naltrexone.
Her daily pain score, as calculated using the Defense and Veterans Pain Rating Scale,
was lower after she was weaned from opioids.
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© 2018 Published by Elsevier Inc.
