A novel neurotherapy of transcranial direct current stimulation (tDCS) combined with cognitive training in ADHD children

      Introduction: The frontline treatment for ADHD is psycho-stimulants, but these are not effective in ∼30% of patients, have side effects and limited long-term efficacy. An alternative treatment might be transcranial direct current stimulation (tDCS), which can lead to long-lasting gains in the function of targeted brain regions by potentiating neural plasticity; underpinned by dopamine and noradrenaline release, which is dysfunctional in ADHD. In ADHD, several small studies showed improved clinical and/or cognitive measures of inattention and inhibition with anodal-tDCS. However, these mainly targeted the dorsolateral prefrontal regions with single session stimulation. The right inferior frontal cortex (rIFC) might be a more optimal target since it is a hub for self-control and attention that is consistently underactive in ADHD and upregulated with psycho-stimulants. Further, multiple sessions paired with cognitive training can prolong tDCS effects for up to 12 months in healthy controls. We conducted the first study targeting the rIFC with multi-session tDCS combined with cognitive training in ADHD children.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'