Neuronavigation and transcranial magnetic stimulation (TMS) are valuable tools in
clinical and research environment. Despite the well-accepted importance of both techniques,
high-cost and low portability of neuronavigation systems, and limited spatial accuracy
of TMS in targeting brain structures limit their applications. Furthermore, existing
TMS neuronavigation software programs are not compatible with multiple tracking devices,
and do not provide an easy-to-implement platform for custom tools. To overcome such
limitations, we developed the open-source, free software InVesalius Navigator for
navigated TMS (https://www.cti.gov.br/en/invesalius). A point-based, co-registration algorithm and a guiding interface were designed
for tracking any TMS coil relative to an individual’s anatomy. The InVesalius Navigator
provides communication with multiple tracking devices, tools for structural image
processing, and online TMS coil tracking, all combined in a user-friendly interface.
Localization, precision errors, and repeatability were measured for the spatial trackers
Patriot (Polhemus Inc.) and MicronTracker Sx60 (ClaroNav Inc.). Additionally, errors
were measured in commercial navigated TMS systems NBS 3.2 and 4.3 (Nexstim Plc.).
InVesalius Navigator provided a localization error of about 1.5 mm, and repeatability
of about 1 mm for translation and 1° for rotation angles. Our results are within the
limits established in the literature and similar to those achieved with the NBS systems.
The developed software provides a flexible platform aiming to fulfill the needs of
research and clinical requirements, expanding the use of navigated TMS throughout
the community. Finally, InVesalius Navigator might improve the reliability and spatial
accuracy of non-invasive brain stimulation measurements.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Brain Stimulation: Basic, Translational, and Clinical Research in NeuromodulationAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Article info
Publication history
960
Identification
Copyright
© 2018 Published by Elsevier Inc.