Effects of acute and subacute stimulation of ventral subthalamic nucleus on cognition and perceptual decision-making in patients with Parkinson’s disease

      The subthalamic nucleus (STN) has direct and indirect connections to prefrontal cortices, and is a commonly accessed region in surgical Parkinson’s Disease (PD) patients, making it an attractive target for modulation of cognitive functions. Here, we studied the effects of acute and subacute (48hr) STN stimulation on cognitive (Stroop) and perceptual decision-making (random dot motion, RDM) tasks.
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