Multimedia Library
Safety, tolerability and effectiveness of a novel 20 Hz rTMS protocol targeting dorsomedial prefrontal cortex in major depression: An open-label case series
Repetitive transcranial magnetic stimulation (rTMS) of the dorsomedial prefrontal cortex (DMPFC) in treatment-resistant depression (TRD) has been recently studied as an alternative to conventional dorsolateral prefrontal cortex (DLPFC) rTMS [1,2]. Across both targets, intermittent theta-burst stimulation (iTBS) reduces treatment duration while achieving comparable outcomes to conventional 10 Hz stimulation [1,3]. However, iTBS can require more costly devices than conventional high-frequency rTMS, and the consistency of excitatory effect varies across individuals [4].Inferior thalamic peduncle deep brain stimulation for treatment-refractory obsessive-compulsive disorder: A phase 1 pilot trial
Several different surgical procedures targeting the limbic circuit have been utilized for severe, treatment resistant obsessive-compulsive disorder; however, there has only been limited exploration of the inferior thalamic peduncle (ITP). The aim of this study was to determine the safety and initial efficacy of ITP deep brain stimulation (DBS) in patients with severe obsessive-compulsive disorder.Deep Brain Stimulation Modulates Gamma Oscillations and Theta–Gamma Coupling in Treatment Resistant Depression
Deep brain stimulation (DBS) in the subcallosal cingulate gyrus (SCG) is becoming an effective therapeutic option for treatment resistant depression (TRD).rTMS of the Dorsomedial Prefrontal Cortex for Major Depression: Safety, Tolerability, Effectiveness, and Outcome Predictors for 10 Hz Versus Intermittent Theta-burst Stimulation
Conventional rTMS protocols for major depression commonly employ stimulation sessions lasting >30 min. However, recent studies have sought to improve costs, capacities, and outcomes by employing briefer protocols such as theta burst stimulation (iTBS).
