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Brain Stimulation Journal
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    • Laakso, IlkkaRemove Laakso, Ilkka filter
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    Article Type

    • Research Article5

    Publication Date

    • Last 5 Years3
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    Author

    • Hirata, Akimasa5
    • Ugawa, Yoshikazu3
    • Murakami, Takenobu2
    • Tanaka, Satoshi2
    • de Santis, Valerio1
    • Gomez-Tames, Jose1
    • Hamasaka, Atsushi1
    • Hontani, Hidekata1
    • Koyama, Soichiro1
    • Maki, Toyohiro1
    • Mikkonen, Marko1
    • Nagata, Tatsuya1
    • Yokota, Tatsuya1

    Journal

    • Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation5

    Keyword

    • Transcranial magnetic stimulation3
    • Electric field2
    • Motor cortex2
    • Brain atlas1
    • Computer simulation1
    • Deep neural networks1
    • Electric field estimation1
    • Finite element analysis1
    • Finite-element method1
    • Focality1
    • HD-TDCS1
    • Inter-subject variability1
    • Interindividual variability1
    • Magnetic resonance image1
    • Motor evoked potentials1
    • Optimization of coil orientation1
    • Patient-specific modeling1
    • Personalized stimulation1
    • TDCS1
    • tDCS1
    • Volume conductor modeling1

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    • Research Article
      Open Access

      Cost of focality in TDCS: Interindividual variability in electric fields

      Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
      Vol. 13Issue 1p117–124Published online: October 2, 2019
      • Marko Mikkonen
      • Ilkka Laakso
      • Satoshi Tanaka
      • Akimasa Hirata
      Cited in Scopus: 48
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        In transcranial direct current stimulation (TDCS), electric current is applied via two large electrodes to modulate brain activity. Computational models have shown that large electrodes produce diffuse electric fields (EFs) in the brain, which depends on individual head and brain anatomy. Recently, smaller electrodes as well as novel electrode arrangements, including high-definition TDCS (HD-TDCS) montages, have been introduced to improve the focality of EFs. Here, we investigated whether the EFs of focal montages are more susceptible to interindividual anatomical differences.
        Cost of focality in TDCS: Interindividual variability in electric fields
      • Research Article
        Open Access

        Real-time estimation of electric fields induced by transcranial magnetic stimulation with deep neural networks

        Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
        Vol. 12Issue 6p1500–1507Published online: June 17, 2019
        • Tatsuya Yokota
        • Toyohiro Maki
        • Tatsuya Nagata
        • Takenobu Murakami
        • Yoshikazu Ugawa
        • Ilkka Laakso
        • and others
        Cited in Scopus: 18
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          Transcranial magnetic stimulation (TMS) plays an important role in treatment of mental and neurological illnesses, and neurosurgery. However, it is difficult to target specific brain regions accurately because the complex anatomy of the brain substantially affects the shape and strength of the electric fields induced by the TMS coil. A volume conductor model can be used for determining the accurate electric fields; however, the construction of subject-specific anatomical head structures is time-consuming.
          Real-time estimation of electric fields induced by transcranial magnetic stimulation with deep neural networks
        • Research Article

          Atlas of optimal coil orientation and position for TMS: A computational study

          Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
          Vol. 11Issue 4p839–848Published online: April 17, 2018
          • Jose Gomez-Tames
          • Atsushi Hamasaka
          • Ilkka Laakso
          • Akimasa Hirata
          • Yoshikazu Ugawa
          Cited in Scopus: 40
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            Transcranial magnetic stimulation (TMS) activates target brain structures in a non-invasive manner. The optimal orientation of the TMS coil for the motor cortex is well known and can be estimated using motor evoked potentials. However, there are no easily measurable responses for activation of other cortical areas and the optimal orientation for these areas is currently unknown.
            Atlas of optimal coil orientation and position for TMS: A computational study
          • Research Article

            Where and what TMS activates: Experiments and modeling

            Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
            Vol. 11Issue 1p166–174Published online: September 26, 2017
            • Ilkka Laakso
            • Takenobu Murakami
            • Akimasa Hirata
            • Yoshikazu Ugawa
            Cited in Scopus: 65
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              Despite recent developments in navigation and modeling techniques, the type and location of the structures that are activated by transcranial magnetic stimulation (TMS) remain unknown.
              Where and what TMS activates: Experiments and modeling
            • Transcranial Direct Current Stimulation (tDCS)/Transcranial Alternating Current Stimulation (tACS) Original Article

              Inter-subject Variability in Electric Fields of Motor Cortical tDCS

              Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
              Vol. 8Issue 5p906–913Published online: May 7, 2015
              • Ilkka Laakso
              • Satoshi Tanaka
              • Soichiro Koyama
              • Valerio De Santis
              • Akimasa Hirata
              Cited in Scopus: 217
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                The sources of inter-subject variability in the efficacy of transcranial direct current stimulation (tDCS) remain unknown. One potential source of variations is the brain's electric field, which varies according to each individual's anatomical features.
                Inter-subject Variability in Electric Fields of Motor Cortical tDCS
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