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    • Research Article5
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    • Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation8

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    • Transcranial direct current stimulation3
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    • Research Article

      Modulation of creativity by transcranial direct current stimulation

      Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
      Vol. 12Issue 5p1213–1221Published online: June 5, 2019
      • Elisabeth Hertenstein
      • Elena Waibel
      • Lukas Frase
      • Dieter Riemann
      • Bernd Feige
      • Michael A. Nitsche
      • and others
      Cited in Scopus: 26
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        Creativity is the use of original ideas to accomplish something innovative. Previous research supports the notion that creativity is facilitated by an activation of the right and/or a deactivation of the left prefrontal cortex. In contrast, recent brain imaging studies suggest that creativity improves with left frontal activation.
        Modulation of creativity by transcranial direct current stimulation
      • Research Article

        Effects of cerebellar transcranial direct current stimulation on cerebellar-brain inhibition in humans: A systematic evaluation

        Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
        Vol. 12Issue 5p1177–1186Published online: April 22, 2019
        • Giorgi Batsikadze
        • Zeynab Rezaee
        • Dae-In Chang
        • Marcus Gerwig
        • Stefan Herlitze
        • Anirban Dutta
        • and others
        Cited in Scopus: 36
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          Cerebellar transcranial direct current stimulation (ctDCS) is increasingly used to modulate cerebellar excitability and plasticity in healthy subjects and various patient populations. ctDCS parameters are poorly standardized, and its physiology remains little understood. Our aim was to compare the physiological effects of three different non-target electrode positions (buccinator muscle, supraorbital region, deltoid muscle).
          Effects of cerebellar transcranial direct current stimulation on cerebellar-brain inhibition in humans: A systematic evaluation
        • Research Article

          Differential effects of bifrontal tDCS on arousal and sleep duration in insomnia patients and healthy controls

          Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
          Vol. 12Issue 3p674–683Published online: January 4, 2019
          • Lukas Frase
          • Peter Selhausen
          • Lukas Krone
          • Sulamith Tsodor
          • Friederike Jahn
          • Bernd Feige
          • and others
          Cited in Scopus: 29
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            Arousal and sleep represent basic domains of behavior, and alterations are of high clinical importance.
            Differential effects of bifrontal tDCS on arousal and sleep duration in insomnia patients and healthy controls
          • Research Article

            Anodal transcranial direct current stimulation over the right dorsolateral prefrontal cortex enhances reflective judgment and decision-making

            Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
            Vol. 12Issue 3p652–658Published online: December 7, 2018
            • Daniel R. Edgcumbe
            • Volker Thoma
            • Davide Rivolta
            • Michael A. Nitsche
            • Cynthia H.Y. Fu
            Cited in Scopus: 2
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              Accounts of cognitive processes in judgment and decision-making are frequently based on a dual-process framework, which reflects two qualitatively different types of processing: intuitive (Type 1) and analytical (Type 2) processes.
              Anodal transcranial direct current stimulation over the right dorsolateral prefrontal cortex enhances reflective judgment and decision-making
            • Rapid Communication

              Effects of electrode angle-orientation on the impact of transcranial direct current stimulation on motor cortex excitability

              Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
              Vol. 12Issue 2p263–266Published online: October 25, 2018
              • Águida Foerster
              • Fatemeh Yavari
              • Leila Farnad
              • Asif Jamil
              • Walter Paulus
              • Michael A. Nitsche
              • and others
              Cited in Scopus: 20
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                For effects of transcranial direct current stimulation (tDCS), electrical field distribution and coverage of the target areas play a decisive role.
                Effects of electrode angle-orientation on the impact of transcranial direct current stimulation on motor cortex excitability
              • Letter to the Editor

                Case Report: Successful Treatment of Therapy-Resistant OCD With Application of Transcranial Alternating Current Stimulation (tACS)

                Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
                Vol. 9Issue 3p463–465Published online: March 10, 2016
                • Ansgar Klimke
                • Michael A. Nitsche
                • Konrad Maurer
                • Ursula Voss
                Cited in Scopus: 29
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                  Obsessive compulsive disorder (OCD) is characterized by recurrent intrusive thoughts and impulses (obsessions), followed by repetitive thinking or behavioral acting (compulsions) which reduces the obsession-associated anxiety level. Without treatment, severity and daily duration of compulsive symptoms often increase, eventually resulting in marked social impairment and loss of employment. Psychopharmacological treatment with serotonin re-uptake inhibitors, and tricyclic antidepressants like clomipramine, which seems to be as effective as cognitive behavior therapy (CBT) leads to symptom reduction in 40–70%, and full recovery in approximately 25% of patients [1].
                • Letter to the Editor

                  The Role of Contact Media at the Skin-electrode Interface During Transcranial Direct Current Stimulation (tDCS)

                  Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
                  Vol. 7Issue 5p762–764Published online: June 20, 2014
                  • Ulrich Palm
                  • Katrina B. Feichtner
                  • Alkomiet Hasan
                  • Gerd Gauglitz
                  • Berthold Langguth
                  • Michael A. Nitsche
                  • Daniel Keeser
                  • Frank Padberg
                  Cited in Scopus: 51
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                    tDCS can be considered to be safe with little side-effects when using defined parameters (e.g. current strength, duration of application, frequency of stimulation). However, skin lesions have been reported in single cases after tDCS application with tap water soaked sponges on both cathodal [1,2] and anodal sites [3] in different laboratories. As potential mechanisms, tissue burning by drying-out of sponge electrodes [4], bacterial superinfection, toxic reaction by tap water constituents (e.g. regionally elevated concentration of specific ions) or impurities [2], toxic electrochemical reaction products [5] or pH changes in the skin milieu [6] have been discussed.
                    The Role of Contact Media at the Skin-electrode Interface During Transcranial Direct Current Stimulation (tDCS)
                  • Transcranial Direct Current Stimulation (tDCS) and Other Methods Original Article

                    Induction of Late LTP-Like Plasticity in the Human Motor Cortex by Repeated Non-Invasive Brain Stimulation

                    Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation
                    Vol. 6Issue 3p424–432Published online: June 4, 2012
                    • Katia Monte-Silva
                    • Min-Fang Kuo
                    • Silvia Hessenthaler
                    • Shane Fresnoza
                    • David Liebetanz
                    • Walter Paulus
                    • and others
                    Cited in Scopus: 537
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                      Non-invasive brain stimulation enables the induction of neuroplasticity in humans, however, with so far restricted duration of the respective cortical excitability modifications. Conventional anodal transcranial direct current stimulation (tDCS) protocols including one stimulation session induce NMDA receptor-dependent excitability enhancements lasting for about 1 h.
                      Induction of Late LTP-Like Plasticity in the Human Motor Cortex by Repeated Non-Invasive Brain Stimulation
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