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Combination of lithium and electroconvulsive therapy (ECT) is associated with higher odds of delirium and cognitive problems in a large national sample across the United States
Lithium is a helpful adjunct to patients undergoing ECT. However, only case reports and limited data suggest increase risk of delirium. Thus, this continues to be a controversial issue.The effect of electroconvulsive therapy on cerebral monoamine oxidase A expression in treatment-resistant depression investigated using positron emission tomography
Electroconvulsive therapy (ECT) constitutes one of the most effective antidepressant treatment strategies in major depression (MDD). Despite its common use and uncontested efficacy, its mechanism of action is still insufficiently understood. Previously, we showed that ECT is accompanied by a global decrease of serotonin-1A receptors in MDD; however, further studies to investigate the involvement of the serotonergic system in the mechanism of action of ECT are warranted. The monoamine oxidase A (MAO-A) represents an important target for antidepressant treatments and was found to be increased in MDD.Electroconvulsive therapy induced gray matter increase is not necessarily correlated with clinical data in depressed patients
Electroconvulsive therapy (ECT) and depression have been associated with brain volume changes, especially in the hippocampus and the amygdala.BDNF plasma levels and genotype in depression and the response to electroconvulsive therapy
Brain derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of depression and the antidepressant response. Electroconvulsive therapy (ECT) is reported to increase BDNF levels in blood, though only a small number of studies have been conducted to date.Episodic memory following deep brain stimulation of the ventral anterior limb of the internal capsule and electroconvulsive therapy
Electroconvulsive Therapy (ECT) and Deep Brain Stimulation (DBS) are effective treatments for patients with treatment-resistant depression (TRD). However, a common side effect of ECT is autobiographical memory loss (e.g., personal experiences), whereas the impact of DBS on autobiographical memories has never been established.Neuromodulation in response to electroconvulsive therapy in schizophrenia and major depression
Electroconvulsive therapy (ECT) is one of the most effective treatments in severe and treatment-resistant major depressive disorder (MDD). ECT has been also shown to be effective in schizophrenia (SZ), particularly when rapid symptom reduction is needed or in cases of resistance to drug-treatment. However, its precise mechanisms of action remain largely unknown.Based on a True Story? The Portrayal of ECT in International Movies and Television Programs
Although electroconvulsive therapy (ECT) is the most effective biological treatment in modern psychiatry, it remains controversial. The cinematic portrayal of ECT has probably shaped the attitudes of millions of viewers [1]. Movies remain an important source of public information [2], and watching ECT scenes has a profound influence on the viewers' opinion of ECT [3]. In a sample of medical students, it was demonstrated to decrease both understanding of and support for ECT [3].Modulation of Limbic and Prefrontal Connectivity by Electroconvulsive Therapy in Treatment-resistant Depression: A Preliminary Study
Major Depressive Disorder (MDD) is one of the most common psychiatric disorders and a leading cause of disability worldwide [1]. Despite advances in the understanding of its pathophysiology, pharmacological treatments are only partially effective. Indeed, an estimated 30% of patients with MDD continue to suffer from refractory symptoms leading to marked functional impairment [2]. Electroconvulsive therapy (ECT) is a well-established alternative for patients with treatment-resistant depression [3].
